Apolipoprotein E genotyping by capillary electrophoretic analysis of restriction fragments.
نویسندگان
چکیده
We present the genotyping of apolipoprotein (apo) E by means of restriction fragment analysis of amplified genomic DNA by high-performance capillary electrophoresis and a replaceable non-gel-sieving matrix. This procedure streamlines the genotyping of apo E in large-scale population studies because of the automation and speed of capillary electrophoresis.
منابع مشابه
Genetic testing for familial Mediterranean fever in Austria by means of reverse-hybridization teststrips.
poproteins in mouse peritoneal macrophages. J Mol Med 2000;78:217–27. 3. Wenham PR, Sedky A, Spooner RJ. Apolipoprotein E phenotyping: a word of caution. Ann Clin Biochem 1991;28:599–605. 4. Hixson JE, Vernier DT. Restriction isotyping of human apolipoprotein E by gene amplification and cleavage with HhaI. J Lipid Res 1990;31:545–8. 5. Somsen GW, Welten HT, Mulder FP, Swart CW, Kema IP, de Jong...
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ورودعنوان ژورنال:
- Clinical chemistry
دوره 43 8 Pt 1 شماره
صفحات -
تاریخ انتشار 1997